BIOF Supply Cosmetic Grade PDRN CAS No.100403-24-5 PDRN Powder 99% Salmon DNA Deoxyribonucleic Acid for Skin Care

Short Description:

PDRN, short for Polydeoxyribonucleotide, is a derivative of DNA with a molecular weight ranging from 50 to 1500 kDa. It is mainly extracted from the testes of male salmon, such as salmon. PDRN contains 50% double – stranded deoxyribonucleotides, and the two polydeoxyribonucleotide chains are connected by hydrogen bonds between base pairs to form a double – helix structure. Due to its high similarity (over 95%) in base composition to human DNA, it has high compatibility and can participate in the metabolic process of human cells, playing roles in promoting tissue repair and anti – inflammation.


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Product Function

  1. Tissue Repair and Regeneration​
PDRN has a remarkable ability to stimulate cell proliferation and tissue repair. It can activate fibroblasts, which are crucial cells in the production of collagen and extracellular matrix. By enhancing the activity of fibroblasts, PDRN promotes the synthesis of collagen fibers and elastin, thereby accelerating the repair of damaged tissues such as skin wounds, surgical incisions, and damaged organs. For example, in skincare, it helps reduce the appearance of scars and improve skin texture after injury.​
  1. Anti - inflammatory Effects​
PDRN exhibits significant anti - inflammatory properties. It can modulate the immune response by inhibiting the production of pro - inflammatory cytokines. This helps to alleviate inflammation in various tissues. In the context of skin, it can soothe irritated and inflamed skin, making it suitable for treating conditions like acne - related inflammation, rosacea, and skin redness caused by environmental stressors.​
  1. Cellular Protection and Antioxidant Activity​
It acts as an antioxidant, protecting cells from oxidative damage caused by free radicals. PDRN can enhance the activity of endogenous antioxidant enzymes in cells, such as superoxide dismutase (SOD) and catalase. This antioxidant function not only helps in preventing premature cell aging but also contributes to maintaining the overall health and functionality of cells, especially in tissues constantly exposed to oxidative stress, like the skin.

Application

  1. Skincare and Cosmetics​
  • Anti - aging Products: PDRN is widely used in anti - aging skincare products. Its ability to boost collagen synthesis reduces the appearance of wrinkles and fine lines, improves skin elasticity, and gives the skin a more youthful and firm appearance. For instance, PDRN - containing serums and creams are popular among consumers seeking to reverse the signs of aging.​
  • Skin Repair and Soothing Products: As it promotes tissue repair and has anti - inflammatory effects, PDRN is a key ingredient in products designed for sensitive skin, post - sunburn care, and products to repair damaged skin barriers. It helps calm irritated skin, reduce redness, and speed up the recovery process.​
  1. Medical and Healthcare​
  • Wound Healing in Surgery and Traumatology: In medical settings, PDRN can be used to accelerate wound healing after surgical procedures or injuries. It can be applied topically or administered systemically to enhance the repair of damaged tissues, reducing the risk of infection and promoting faster recovery.​
  • Ophthalmology: PDRN has shown potential in ophthalmic applications. It can be used to treat certain eye conditions, such as corneal injuries and dry eye syndrome. By promoting cell repair and reducing inflammation in the eye tissues, it helps improve eye health and function.​
  1. Haircare​
In the haircare industry, PDRN is incorporated into products to promote hair growth. It can stimulate hair follicle cells, increasing blood circulation in the scalp and providing essential nutrients for hair growth. Products like PDRN - based hair serums and shampoos are designed to prevent hair loss and enhance hair thickness and strength.

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