BIOF Supply High Quality 6-Paradol Powder CAS 27113-22-0 1-(4-hydroxy-3-methoxyphenyl)decan-5-one

Short Description:

6-Paradol is a naturally occurring compound found in various plants, particularly in ginger (Zingiber officinale), where it contributes to the spice’s distinctive flavor and aroma. It belongs to a class of compounds known as phenolic ketones, which are known for their potential health benefits. 6-Paradol has gained significant attention in recent years for its promising pharmacological properties, including its potential anti-inflammatory, antioxidant, and anti-cancer effects.

Chemical Structure and Sources: 6-Paradol is a member of the gingerol family, which also includes other bioactive compounds like 6-gingerol and 8-gingerol. It is structurally similar to gingerol but differs in its chemical composition, specifically in the length of its side chain. The compound is most commonly found in ginger, but it is also present in smaller amounts in other plant species, such as turmeric.


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  1. Anti-inflammatory Properties: One of the most widely studied benefits of 6-Paradol is its ability to reduce inflammation. Inflammation is a common underlying factor in many chronic diseases, such as arthritis, cardiovascular disease, and certain types of cancer. Studies suggest that 6-Paradol can inhibit the production of pro-inflammatory cytokines, which are signaling molecules that contribute to inflammation in the body.
  2. Antioxidant Activity: 6-Paradol possesses potent antioxidant properties, meaning it can neutralize free radicals in the body. Free radicals are unstable molecules that can damage cells and contribute to the aging process, as well as the development of diseases such as cancer and neurodegenerative disorders. By combating oxidative stress, 6-Paradol may help protect cells from damage and promote overall health.
  3. Cancer Prevention and Anti-cancer Potential: Research has shown that 6-Paradol may have anti-cancer properties. Studies conducted on animal models and in vitro have suggested that 6-Paradol can induce cell death in certain types of cancer cells, including breast, colon, and prostate cancer cells. Additionally, it may help slow the growth of tumors and reduce the spread of cancer cells.
  4. Weight Management and Metabolism: 6-Paradol has also been studied for its potential role in weight management. Some studies suggest that it can promote fat oxidation and enhance metabolic activity. By increasing the body's ability to burn fat and boost metabolism, 6-Paradol may contribute to weight loss and help individuals maintain a healthy weight.
  5. Neuroprotective Effects: There is growing evidence that 6-Paradol may have neuroprotective effects, which could be beneficial for brain health. Some studies indicate that the compound may help protect neurons from oxidative damage, potentially reducing the risk of neurodegenerative diseases like Alzheimer's and Parkinson's.

Application

  1. Health Supplements: Due to its anti-inflammatory and antioxidant effects, 6-paradol is often studied for use in dietary supplements aimed at reducing oxidative stress and inflammation.
  2. Anticancer Research: Studies have shown that 6-paradol may inhibit the growth of cancer cells, especially in breast, colon, and prostate cancers, making it a subject of ongoing research in cancer therapy.
  3. Flavoring and Fragrance: Being derived from ginger, 6-paradol is used in the food and fragrance industries for its distinct flavor and aroma.
  4. Pain Relief: Some studies suggest 6-paradol may have pain-relieving properties, potentially being used in topical creams or ointments for conditions like arthritis.
  5. Metabolic Health: There is some evidence that 6-paradol might help in managing metabolic disorders, such as obesity, by promoting fat burning and reducing blood sugar levels.

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