Nicotinamide Riboside NR Powder 99% Purity CAS 1341-23-7 NAD+ Booster Supplement Raw Material

Short Description:

Nicotinamide Riboside (NR) is a revolutionary precursor to Nicotinamide Adenine Dinucleotide (NAD+), an essential coenzyme found in every living cell. NAD+ is critical for cellular energy metabolism, mitochondrial function, and DNA repair. As natural NAD+ levels decline significantly with age, supplementation with high-purity NR powder provides an efficient, bioavailable pathway to replenish NAD+ pools, supporting healthy cellular aging and overall vitality.

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Produt Introduction

Nicotinamide Riboside (NR) is a next-generation dietary supplement ingredient and a high-efficiency precursor to Nicotinamide Adenine Dinucleotide (NAD+), designed to support healthy cellular aging and mitochondrial vitality.

I. Mechanism of action

Nicotinamide Riboside can be efficiently converted into NAD+ through the NRK (nicotinamide riboside kinase) pathway within cells. By restoring intracellular NAD+ levels, it activates sirtuin enzymes (SIRT1, SIRT3) and PARPs, optimizes mitochondrial ATP energy production, facilitates cellular DNA repair, and mitigates age-related metabolic decline.

II. Product types

Pure Powder: High-purity crystalline raw material, highly water-soluble, ideal for custom blending, formulation development, and bulk manufacturing.
Capsules & Tablets: The most common oral finished dosage form, offering precise serving sizes and high bio-stability for daily anti-aging regimens.
Sublingual Powder / Lozenges: Designed for rapid absorption through the oral mucosa, bypassing primary hepatic first-pass metabolism.
Functional Beverages & Liquid Sachets: Water-soluble formulas combined with other synergistic longevity compounds (such as Resveratrol or Pterostilbene) for on-the-go vitality drinks.

III. Usage method

When taking capsules or tablets, it is recommended to ingest them with a glass of water in the morning, with or without food, to best align with natural cellular circadian rhythms.
For raw powder formulations, dissolve the specified dosage into water or room-temperature liquid; avoid mixing with hot liquids to prevent thermal degradation.
Standard recommended daily dosage for dietary intake generally ranges between 250 mg to 500 mg per day, or as directed by a healthcare professional.

IV. Precautions

Nicotinamide Riboside is generally well tolerated; mild, infrequent side effects may include slight nausea, mild headaches, fatigue, or minor stomach discomfort. Discontinue use and consult a physician if adverse reactions persist.
Keep the raw material sealed in a cool, dry place away from direct sunlight, high heat, and humidity to ensure optimal chemical stability.
Pregnant or nursing women, individuals under medical supervision, or those with known chronic health conditions should consult a healthcare provider prior to supplementation.

Effect

Boost NAD+ levels and promote healthy aging: Nicotinamide Riboside serves as a direct and highly bioavailable precursor to NAD+. By restoring cellular NAD+ pools, it activates longevity enzymes such as sirtuins (SIRT1, SIRT3) and PARPs, facilitating cellular repair, supporting DNA integrity, and slowing down biological aging processes.
Enhance cellular energy and mitochondrial function: NR optimizes mitochondrial ATP production to fuel vital cellular functions, helping to reduce physical fatigue, boost metabolic rate, and improve overall vitality and exercise endurance.
Support cognitive and cardiovascular health: By protecting neurons against oxidative stress and metabolic decline, NR helps maintain sharp cognitive function and memory. Simultaneously, it supports vascular endothelial health and maintains healthy cardiac resilience.

It should be noted that Nicotinamide Riboside supplements are generally well tolerated, but individual responses may vary; mild and transient side effects such as nausea, headaches, or slight stomach discomfort may occasionally occur.

Certificate Of Analysis

Product Name	Nicotinamide Riboside Chloride	Specification	Company Standard
CAS No.	23111-00-4	Manufacture Date	2026.4.23
Quantity	500KG	Analysis Date	2026.4.29
Batch No.	ES-260423	Expiry Date	2028.4.22
Items	Specifications		Results
Assay (HPLC)	≥98%		99%
Appearance	White or off white or yellowish powder		White powder
Odor & Tasted	Characteristic		Complies
Melting Point	130℃melting decomposition		Complies
Identification	The HPLC spectrum of the sample must be concordant with Test standard		Complies
	Chloride identification reaction		Complies
Acidity	2.5~4.5		3.23
Related Substances	Impurity A≤0.5%		N.D.
	Impurity B≤1.5%		N.D.
	Individual impurity substance ≤3.5%		2.69%
	Total impurity substance ≤5.0%		2.69%
Water Content	≤0.5%		0.14%
Residue on Ignition	≤0.5%		0.05%
Residual Solvents	Methanol ≤3000 ppm		N.D.
	Ethanol ≤5000 ppm		0.04%
Heavy Metal
Total Heavy Metal	≤5 ppm		Complies
Lead(Pb)	≤2.0 ppm		Complies
Arsenic(As)	≤2.0 ppm		Complies
Cadmium (Cd)	≤1.0 ppm		Complies
Mercury(Hg)	≤0.1 ppm		Complies
Microbiological Test
Total Plate Count	≤1000cfu/g		Complies
Yeast & Mold	≤100cfu/g		Complies
E.Coli	Negative		Complies
Salmonella	Negative		Complies
Staphylococcus Aureus	Negative		Complies
Package	Packed in plastic bag inside and aluminum foil bag outside.
Storage	Store in a cool and dry place, keep away from strong light and heat.
Shelf Life	Two years when properly stored.
Conclusion	Sample Qualified.