Product Applications
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Sleep Disorder Management: It is widely used to alleviate insomnia, particularly difficulty falling asleep, by supplementing the body’s natural melatonin levels to signal the onset of sleep.
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Jet Lag Mitigation: Travelers often use it to adjust disrupted circadian rhythms caused by crossing multiple time zones, helping to synchronize sleep patterns with the new local time.
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Irregular Sleep Schedule Support: Individuals with erratic work hours (e.g., shift workers) or inconsistent bedtime routines may use it to establish more regular sleep-wake cycles.
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Pediatric Sleep Assistance: In some cases, under medical guidance, it may be used to help children with sleep issues related to conditions like autism or ADHD, though dosages are strictly controlled.
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Research and Formulation: Beyond direct supplementation, it is used in scientific studies exploring circadian rhythm mechanisms, and as an ingredient in various health products (e.g., combined with vitamins or herbs in sleep-support formulas).
Effect
1.Circadian Rhythm Regulation: It helps synchronize the body’s natural sleep-wake cycle (circadian rhythm) by signaling the brain when it is time to sleep, particularly in response to darkness. This action is crucial for maintaining consistent sleep patterns.
2.Sleep Onset Promotion: By supplementing the body’s endogenous melatonin levels, it can reduce the time it takes to fall asleep (sleep latency), making it effective for individuals with difficulty initiating sleep, such as those with insomnia or disrupted schedules.
3.Jet Lag Alleviation: It aids in resetting the circadian rhythm when it is disrupted by rapid time zone changes, helping the body adapt to a new sleep schedule more quickly and reducing symptoms like daytime fatigue or nighttime restlessness.
4.Antioxidant Properties: Emerging research suggests it may act as a mild antioxidant, potentially helping to neutralize free radicals in the body, though this role is secondary to its primary sleep-regulating function.
5.Potential Immune and Metabolic Support: Some studies indicate it may modestly support immune system function and help regulate certain metabolic processes, though these effects are less established and often require further research.
Certificate Of Analysis
|
Product Name |
Melatonine |
Specification |
Company Standard |
|
CAS No. |
73-31-4 |
Manufacture Date |
2025.6.2 |
|
Quantity |
100KG |
Analysis Date |
2025.6.9 |
|
Batch No. |
BF-250602 |
Expiry Date |
2027.6.1 |
|
Items |
Specifications |
Results |
|
|
Appearance |
White to off-white crystalline powder.Soluble in alcohol,slightly soluble in water |
Conforms |
|
|
Identification |
|||
|
Infrared Absorption |
Positive |
Positive |
|
|
Ultraviolet Absorption |
Positive |
Positive |
|
|
HPLC Identification Test |
Positive |
Positive |
|
|
Assay(Dry Basis) |
98.5-101.5% |
99.78% |
|
|
Loss on Drying(%) |
1.05 % Max |
0.08% |
|
|
Residue on Ignition(%) |
0.02 % Max |
0.01% |
|
|
Melting Point |
116.0-120.0℃ |
118.8-119.9℃ |
|
|
Chloride And Sulfate |
≤0.02% |
Conforms |
|
|
Related Compounds |
Individual Impurities≤0.1% |
0.029% |
|
|
|
Total Impurities≤1.0% |
0.08% |
|
|
Residue Analysis |
|||
|
Lead(Pb) |
≤1.0ppm |
Conforms |
|
|
Arsenic (As) |
≤1.0ppm |
Conforms |
|
|
Cadmium (Cd) |
≤0.5ppm |
Conforms |
|
|
Mercury (Hg) |
≤0.1ppm |
Conforms |
|
|
Conclusion |
Conform with the requirement of USP40 Standard |
||
Inspection personnel:Yan Li Review personnel:Lifen Zhang Authorized personnel:LeiLiu
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